Unclassified oesophageal motor disorders simulating achalasia.

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Unclassified oesophageal motor disorders simulating achalasia.

Achalasia of the oesophagus is characterized by the absence of peristalsis, failure of the inferior oesophageal sphincter to relax after swallowing (Harris, 1966), and a positive mecholyl test (Kramer and Ingelfinger, 1951). This combination offeatures is regarded as specific for this disease. Nevertheless, in the literature a number of cases have been designated achalasia despite the presence ...

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Familial infantile oesophageal achalasia.

Oesophageal achalasia is uncommon in children and in its familial form it is a rarity. The presentation and management of two male siblings who presented with oesophageal achalasia as infants are reported. A high degree of consanguinity in the parents of the children existed, suggesting autosomal recessive transmission.

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Effect of sildenafil on oesophageal motor function in healthy subjects and patients with oesophageal motor disorders.

BACKGROUND AND AIMS Sildenafil blocks phosphodiesterase type 5 which degrades nitric oxide (NO) stimulated 3'5'-cyclic monophosphate (cGMP), thereby relaxing smooth muscle cells in various organs. We used sildenafil as a tool to investigate the role of the NO-cGMP pathway in the oesophagus of healthy volunteers and patients with hypercontractile oesophageal motility disorders. METHODS Six hea...

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Selective pulmonary fat aspiration complicating oesophageal achalasia.

A 53 year old woman was referred with an 18 month history of dry cough and exertional breathlessness. There was a past history of oesophageal achalasia. Examination revealed fine right sided inspiratory crepitations only, and pulmonary function tests showed a restrictive defect with a transfer factor of 59% predicted. A chest CT scan showed extensive bilateral ground glass opacification with in...

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Congenital oesophageal achalasia in the dog.

A 3-month-old German shepherd puppy with a congenitally dilated oesophagus had radiographic, cinefluoroscopic, and oesophageal motility studies before a modified Heller operation was performed. Subsequent examination of the oesophagus revealed no ganglion cells, and the condition was considered to be identical with human achalasia. In dogs, this appears to be more common in the German shepherd ...

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ژورنال

عنوان ژورنال: Gut

سال: 1969

ISSN: 0017-5749

DOI: 10.1136/gut.10.3.234